A tale of two toxicities: malformed selenoproteins and oxidative stress both contribute to selenium stress in plants
Identifieur interne : 000F71 ( Main/Exploration ); précédent : 000F70; suivant : 000F72A tale of two toxicities: malformed selenoproteins and oxidative stress both contribute to selenium stress in plants
Auteurs : Doug Van HoewykSource :
- Annals of Botany [ 0305-7364 ] ; 2013.
Abstract
Despite selenium's toxicity in plants at higher levels, crops supply most of the essential dietary selenium in humans. In plants, inorganic selenium can be assimilated into selenocysteine, which can replace cysteine in proteins. Selenium toxicity in plants has been attributed to the formation of non-specific selenoproteins. However, this paradigm can be challenged now that there is increasingly abundant evidence suggesting that selenium-induced oxidative stress also contributes to toxicity in plants.
This Botanical Briefing summarizes the evidence indicating that selenium toxicity in plants is attributable to both the accumulation of non-specific selenoproteins and selenium-induced oxidative stress. Evidence is also presented to substantiate the claim that inadvertent selenocysteine replacement probably impairs or misfolds proteins, which supports the malformed selenoprotein hypothesis. The possible physiological ramifications of selenoproteins and selenium-induced oxidative stress are discussed.
Malformed selenoproteins and oxidative stress are two distinct types of stress that drive selenium toxicity in plants and could impact cellular processes in plants that have yet to be thoroughly explored. Although challenging, deciphering whether the extent of selenium toxicity in plants is imparted by selenoproteins or oxidative stress could be helpful in the development of crops with fortified levels of selenium.
Url:
DOI: 10.1093/aob/mct163
PubMed: 23904445
PubMed Central: 3783228
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000C10
- to stream Pmc, to step Curation: 000C09
- to stream Pmc, to step Checkpoint: 000B64
- to stream Ncbi, to step Merge: 001372
- to stream Ncbi, to step Curation: 001372
- to stream Ncbi, to step Checkpoint: 001372
- to stream Main, to step Merge: 000F76
- to stream Main, to step Curation: 000F71
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A tale of two toxicities: malformed selenoproteins and oxidative stress both contribute to selenium stress in plants</title>
<author><name sortKey="Van Hoewyk, Doug" sort="Van Hoewyk, Doug" uniqKey="Van Hoewyk D" first="Doug" last="Van Hoewyk">Doug Van Hoewyk</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">23904445</idno>
<idno type="pmc">3783228</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783228</idno>
<idno type="RBID">PMC:3783228</idno>
<idno type="doi">10.1093/aob/mct163</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">000C10</idno>
<idno type="wicri:Area/Pmc/Curation">000C09</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000B64</idno>
<idno type="wicri:Area/Ncbi/Merge">001372</idno>
<idno type="wicri:Area/Ncbi/Curation">001372</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001372</idno>
<idno type="wicri:doubleKey">0305-7364:2013:Van Hoewyk D:a:tale:of</idno>
<idno type="wicri:Area/Main/Merge">000F76</idno>
<idno type="wicri:Area/Main/Curation">000F71</idno>
<idno type="wicri:Area/Main/Exploration">000F71</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A tale of two toxicities: malformed selenoproteins and oxidative stress both contribute to selenium stress in plants</title>
<author><name sortKey="Van Hoewyk, Doug" sort="Van Hoewyk, Doug" uniqKey="Van Hoewyk D" first="Doug" last="Van Hoewyk">Doug Van Hoewyk</name>
</author>
</analytic>
<series><title level="j">Annals of Botany</title>
<idno type="ISSN">0305-7364</idno>
<idno type="eISSN">1095-8290</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Despite selenium's toxicity in plants at higher levels, crops supply most of the essential dietary selenium in humans. In plants, inorganic selenium can be assimilated into selenocysteine, which can replace cysteine in proteins. Selenium toxicity in plants has been attributed to the formation of non-specific selenoproteins. However, this paradigm can be challenged now that there is increasingly abundant evidence suggesting that selenium-induced oxidative stress also contributes to toxicity in plants.</p>
</sec>
<sec><title>Scope</title>
<p>This Botanical Briefing summarizes the evidence indicating that selenium toxicity in plants is attributable to both the accumulation of non-specific selenoproteins and selenium-induced oxidative stress. Evidence is also presented to substantiate the claim that inadvertent selenocysteine replacement probably impairs or misfolds proteins, which supports the malformed selenoprotein hypothesis. The possible physiological ramifications of selenoproteins and selenium-induced oxidative stress are discussed.</p>
</sec>
<sec><title>Conclusions</title>
<p>Malformed selenoproteins and oxidative stress are two distinct types of stress that drive selenium toxicity in plants and could impact cellular processes in plants that have yet to be thoroughly explored. Although challenging, deciphering whether the extent of selenium toxicity in plants is imparted by selenoproteins or oxidative stress could be helpful in the development of crops with fortified levels of selenium.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Van Hoewyk, Doug" sort="Van Hoewyk, Doug" uniqKey="Van Hoewyk D" first="Doug" last="Van Hoewyk">Doug Van Hoewyk</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/OrangerV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F71 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000F71 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Bois |area= OrangerV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:3783228 |texte= A tale of two toxicities: malformed selenoproteins and oxidative stress both contribute to selenium stress in plants }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23904445" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a OrangerV1
This area was generated with Dilib version V0.6.25. |